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Roche reported positive Phase II topline data showing that its once-weekly dual glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide receptor agonist CT-388 achieved substantial, sustained, and dose-dependent weight loss through 48 weeks
The percentage of GLP- 1R positive cases for Inspos, Insneg, and insulinoma was 31%, 0%, and 84%, respectively
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Berberine and GLP-1 receptor agonists are distinct compounds with different mechanisms of action
