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Certain microbes ferment fiber into short-chain fatty acids like butyrate, which directly stimulate GLP-1 release from intestinal L-cells and improve glucose control, appetite signaling, and metabolism

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Corresponding EHR data for UKBB participants were sourced from the UK Biobank Resource, which operates under the auspices of the UK Biobank Steering Committee and has received ethical approval from the North West Multi-centre Research Ethics Committee