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Over time, these processes gradually become less efficient, leading to the accumulation of biological changes that affect metabolism, tissue function, and resilience across organ systems
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Interestingly, only a very small amount of GLP-1R is present in the -cell membrane, but GLP-1 can inhibit glucagon secretion in human pancreatic islets by directly acting on GLP-1R on -cells
J Neurol Neurosurg Psychiatry 89(10):10881100 Mollan SP et al (2019) The expanding burden of idiopathic intracranial hypertension
