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Many individuals with well-controlled hypothyroidism on levothyroxine replacement therapy continue to struggle with weight management
Accordingly, the central infusion of exendin-4, a GLP-1R agonist, increased the sympathetic tone of the fibers innervating the BAT, resulting in activation of thermogenesis in both lean and obese mice

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Better sleep reduces the severity of obstructive sleep apnea (New England Journal of Medicine, 2024)

Cost and coverage remain the biggest access barriers
