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Description
At equivalent diabetes doses, the two medications produce very similar GI side effect rates

Individuals with liver disease should exercise caution, as rare cases of liver injury have been reported, and berberine undergoes hepatic metabolism

You begin at a low dose and gradually titrate up over several weeks to minimize gastrointestinal side effects and allow your body to adjust

Digestive side effects are common, especially early on, and can range from mild to disruptive

doi: 10.1001/jama.2019.2942
