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[1] [2] It works by mimicking the action of the naturally occurring hormone GLP-1, which stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and reduces appetite

It belongs to a group of drugs called GLP-1 receptor agonists, which help control blood sugar levels by: These effects have made it useful not only for diabetes but also for weight management-especially in people with obesity

, 2015 European Medicines Agency(EMA)

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The glucose transporter type 1 (GLUT1), the large neutral amino-acid transporter type 1 (LAT1), the cationic amino-acid transporter type 1 (CAT1), the monocarboxylic acid transporter type 1 (MCT1), and the equilibrative nucleoside transporter 1 (ENT1) are some of the most commonly endogenous carrier-mediated BBB transporters used as carrier systems employed for drug delivery [19]