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Important safety advice : Never stop Rybelsus abruptly without medical guidance Arrange follow-up with your GP within 2 to 4 weeks of discontinuation Monitor blood glucose levels as advised by your healthcare team Women planning pregnancy should stop Rybelsus at least 2 months before conception If switching to another GLP-1 receptor agonist, follow your clinician's guidance on timing to avoid gaps in glycaemic control Continue healthy eating and physical activity habits Seek urgent medical help if you experience : Severe, persistent abdominal pain (possible pancreatitis) Signs of diabetic ketoacidosis (DKA): nausea, vomiting, abdominal pain, rapid breathing, confusion, fruity breath odour Marked hyperglycaemia or ketones in urine/blood Visual changes, especially if you have diabetic retinopathy If you are considering stopping Rybelsus due to side effects, discuss this with your healthcare provider first, as dose adjustment or symptomatic management strategies may allow continued treatment

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In the GLP-1 agonist group the mean (SD) age was 55.3 (12.3), 3933 (63%) female, 4554 (72.9%) white, while in the control group the mean (SD) age was 55.5 (13.5), 4025 (64.5%) female, and 4511 (72.3%) white

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