do you keep semaglutide refrigerated Storage Guide: Does It Need to Be Refrigerated? 7 Medications That Require Refrigeration

This is a distinguishing factor from the traditional, secretagogue class of drugs used in the treatment of Type 2 DM, which are not glucose-dependent and therefore carry a risk of hypoglycemia

Similarly, participants in an extended semaglutide trial, who lost an average of 17.3% of their body weight after more than one year of receiving the drug and making lifestyle changes, regained about two-thirds of that lost weight after one year without any clinical-trial interventions 2

Researchers focused on GLP-1, a naturally occurring hormone released in the gut after eating, because of its ability to stimulate insulin secretion in a glucose-dependent manner and suppress excess glucagon

Compounded medication disclaimer: Highland Longevity prescribes compounded semaglutide only

"The FDA regulates brand-name GLP-1 drugs such as semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro, Zepbound) and approves those drugs in very specific doses," says Katy Williams, MD, an MU Health Care family medicine doctor and bariatric medicine specialist