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Functional MRI studies have shown that people on GLP-1 therapy show reduced activation in brain reward centers when viewing food images

Studies indicate that GLP-1 users consume 20% to 30% less energy, and the impact is particularly pronounced in junk food and other high-calorie foods

Clinical Trials and Safety Profile: In 2006, dipeptidyl-peptidase-4 (DPP-4) inhibitors were launched for the treatment of type 2 diabetes

Treatment with exenatide has been shown to decrease food intake and attenuate food-related neural responses in key regions such as the insula, amygdala, putamen, and orbitofrontal cortex (van Bloemendaal et al., 2014)

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