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A box containing Zepbound (tirzepatide) injection pens in Boston, MA on November 16, 2025

Up to now, most explanations have centered on the brain, lower dopamine signaling, reduced craving, less reactivity to alcohol cues in reward regions like the ventral tegmental area and nucleus accumbens

This once-weekly weight loss injection works by suppressing the appetite- so you feel full longer.

Learn about side effects, appetite changes, and tips for a successful first week.

Eating less on Wegovy but worried about muscle loss
