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Show Notes GLP-1 drugs, like Mounjaro and Wegovy , are in the headlines almost every day as potential treatments for everything from fibromyalgia to addiction to arthritis

Discontinuation rates remain below 5%

10.1016/j.bbr.2015.07.024 [DOI] [PubMed] [Google Scholar] Milaneschi Y, Simmons WK, van Rossum EFC, Penninx BW (2019) Depression and obesity: evidence of shared biological mechanisms
The majority of GLP-1RA treatment regimens reported nausea as the most frequent gastrointestinal side effect, particularly when beginning a GLP-1 or shortly following dose

2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes: developed by the task force on the management of cardiovascular disease in patients with diabetes of the European Society of Cardiology (ESC)
