glp-1 and kidneys agonists in the treatment of chronic kidney disease in type 2 diabetes obesity Frontiers | GLP-1 Receptor Agonists

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Glucose-dependent insulinotropic polypeptide may enhance fatty acid re-esterification in subcutaneous abdominal adipose tissue in lean humans

Abbreviations ACC: American College of Cardiology ADA: American Diabetes Association ASCVD: Atherosclerotic cardiovascular disease BMI: Body mass index CI: Confidence interval CV: Cardiovascular CVD: Cardiovascular disease CVOT: Cardiovascular outcomes trial DPP-4: Dipeptidyl peptidase-4 EASD: European Association for the Study of Diabetes EDTA: European Dialysis and Transplant Association eGFR: Estimated glomerular filtration rate ERA: European Renal Association ESC: Europe Society of Cardiology ESRD: End-stage renal disease EURECA-m: European Renal and Cardiovascular Medicine FDA: U.S

Additional studies have indicated that GLP-1 enhances endothelial function in diabetic vasculature by reducing endothelial permeability and contractility, while also offering protection against oxidative stress and autophagic processes [111,112]

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