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One rat treated with exenatide died of pancreatic necrosis, and other animals had findings of acinar-to-ductal metaplasia and foci of ductal hyperplasia, which were interpreted as premalignant changes 6,7

Better sleep yields more energy for exercising, for instance, and helps regulate those appetite hormones, ghrelin and leptin

beta-cell failure in diabetes and preservation by clinical treatment

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Curr Diabetes Rev 14(3):273279 Mousavi A et al (2025) Safety, efficacy, and cardiovascular benefits of combination therapy with SGLT-2 inhibitors and GLP-1 receptor agonists in patients with diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials
