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Cardiovascular risk reduction persisted throughout the study period

As in prior experiments with GEP44, no indicators of nausea or malaise (e.g., changes in responsiveness, behavior, coat appearance, or facial expressions such as orbital tightening and nose/cheek flattening) were observed with GEP12 dosing

Any severe or persistent reaction, especially spreading redness or intense pain, should be reported quickly so the provider can evaluate for allergy or infection

Reactive microglia are positive for HLA-DR in the: Substantia nigra of Parkinsons and Alzheimers disease brains

Set a Threshold for Protocol Pause Define an a priori stopping rule before beginning research