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This phase 3 multicenter study, which is coordinated by Cleveland Clinics C5Research academic research organization, is enrolling 15,000 adults with overweight or obesity (BMI 27) who do not have diabetes but do have either established CVD or multiple CVD risk factors

Read this next 'Night Owls' At Risk Of Wider Waistlines, Unhealthy Hearts THURSDAY, July 16, 2026 Higher levels of cholesterol and body fat are more likely in folks who stay up late, new research finds

De meest voorkomende bijwerkingen zijn misselijkheid, braken, diarree of obstipatie en een vol gevoel

When doctors prescribe a drug off-label, they base this decision on their clinical judgment, sometimes influenced by emerging research or patient reports that suggest the drug might help with an unapproved condition

However, the available information suggests that there is no significant interaction that would cause concern