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Int J Endocrinol 2020

However, in a study of over 390 patients, 10% of whom had type 1 diabetes, although symptoms improved over a 12-week period, there was dose-dependent worsening of glycemic control in 14% of subjects [127]

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In those same studies, a subset of patients around 10% to 15% lost less than 5% of their body weight, the threshold often used to define meaningful weight loss