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The FDA approval acknowledges that GLP-1 receptor agonists can play a vital role in reducing the risk of Major Adverse Cardiovascular Events (MACE), such as heart attack, stroke, and cardiovascular death, particularly in adults with established cardiovascular disease and obesity or overweight
A family or personal history of thyroid cancer

It enhances insulin secretion, suppresses glucagon release, slows gastric emptying, and modulates appetite, providing a synergistic effect on metabolic regulation

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