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Discontinuation: If symptoms are severe, persistent, or suggestive of hypersensitivity, discontinuing the medication may be necessary

The therapy may also increase muscle mass, reduce body fat, and enhance exercise performance, supporting an active lifestyle

254 Thalidomide is an immunomodulatory glutamate derivative that significantly reduces the protein expression levels of p-AKT and p-PI3K in intestinal epithelial cells and exerts anti-inflammatory effects by suppressing the activation of the PI3K/AKT pathway

Treatment typically begins at 0.25 mg for four weeks before increasing in steps to 0.5 mg, 1.0 mg, 1.7 mg, and eventually 2.4 mg

Additionally, post-surgery patients should be mindful of their medication absorption