severe diarrhea on tirzepatide vs. Semaglutide: What You Should Know Tirzepatide – Josey Medical Clinic:

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Semaglutide (Wegovy, Ozempic) received FDA approval for chronic weight management in 2021, followed by tirzepatide (Zepbound) in 2023, both demonstrating substantial weight loss in clinical trials

While its not yet approved in Ireland, Retatrutide is currently in late-stage clinical trials, with availability expected from 2026 onwards