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This can help improve emotional eating and general overeating

An investigation of the dual GLP-1R and neuropeptide Y2-receptor agonist, GEP44, found that this drug attenuated opioid taking and seeking at a dose that did not suppress food intake in rats 89

Beyond heart rate concerns, the combination creates a cascade of overlapping side effects: nausea from semaglutide paired with appetite suppression from phentermine can lead to inadequate calorie and nutrient intake

doi: 10.1089/thy.2015.042234 83 MorelliSReboldiGMorettiSMenicaliEAveniaNPuxedduE