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Omene C., Kowzun M., Kumar S., et al., Feasibility Study of Tirzepatide for Weight Loss Intervention in Early Stage Hormone Receptor Positive/HER2 Negative Breast Cancer, Presented at the San Antonio Breast Cancer Symposium (SABCS)

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AstraZeneca has also developed an alternative formulation for oral administration of a peptide-based antdiabetic therapeutic, which has been directly compared to oral semaglutide in terms of pharmacokinetics, bioavailability, and clinical efficacy

16 Risk of nutrient deficiencies: GLP-1 agonists significantly reduce appetite, gastrointestinal motility, and nutrient absorption, leading to reduced calorie and protein intake