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The question, as with combining GLP-1 and GIP receptor activity, is whether adding glucagon receptor activity to GLP-1 receptor activity exceeds the glycaemic lowering and weight loss achieved with a GLP-1 RA alone (Ambury et al, 2018
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Weight loss drugs: What do we know so far
Tirzepatide, found in medications like Mounjaro and Zepbound, works on two different hormone receptors (GLP-1 and GIP)
It is also essential to stay hydrated and avoid carbonated beverages, as these can contribute to hiccups
