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Discoveries of GIP and GLP-1 The first incretin, GIP, was purified from canine intestinal extracts in the late 1960s (8) and initially named gastric inhibitory polypeptide (9) because the peptide inhibited gastrin-stimulated H + secretion (10)

This is why compounded tirzepatide dosing is ideally personalized, not prescriptive

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The label on GLP-1 medications say they are to be used in combination with a reduced-calorie diet and increased physical activity, said Geoff Cook, Chief Executive Officer of Noom