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Description
Purpose of Review: This article summarizes the medical management of obesity with an emphasis on incretin-based therapeutics that target the neuro-hormonal basis of obesity.Recent Findings: Medications that mimic the effect of incretins, a group of peptide hormones released in response to nutrient intake that regulate appetite, result in potent and durable weight loss

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Research on the experimental drug petrelintide suggests it is much less likely to cause nausea and vomiting than GLP-1 drugs, but the pace of weight loss is more moderate.
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