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Breaking this cycle will require evidence-based, patient-centric policies that recognize obesity as a chronic, relapsing condition, along with integrated care models that combine ongoing pharmacotherapy, lifestyle interventions, and robust patient support

Caloric Surplus Consuming more calories than the body expends, creating conditions that support tissue growth (both muscle and fat)

10.1016/S0140-6736(08)61246-5 44 GaultV

We herein highlight some timely gaps and recommendations based on limited available evidence and expert opinion to help guide clinicians in addressing real-world questions raised in practice

Frontiers in Neuroenergetics, March 2013