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Eligibility for Semaglutide GLP-1 typically includes individuals with a BMI of 30 or higher (obese) or those overweight with a BMI of 27 or higher who also have at least one weight-related health condition

Figure 3 Discussion In this large-scale real-world cohort study emulating a target trial, we evaluated the comparative dermatologic outcomes associated with initiation of GLP-1 receptor agonists versus DPP-4 inhibitors among patients with T2DM

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Although these therapies offer distinct mechanisms, their clinical translation remains limited by safety concerns, poor translatability, and inadequate weight-loss efficacy as monotherapies
