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The use of glucagon-like peptide 1 receptor agonist (GLP-1 RA) medications, originally developed for the management of type 2 diabetes, has surged in recent

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Finally, we demonstrate that in mice, both the efficacy and tolerability of GLP1R agonists vary with the phase of the estrous cycle, being highest during proestrus (when estrogen levels peak) and lowest in diestrus (low estrogen levels)