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How Semaglutide Causes Weight Loss and Affects Bile Composition Semaglutide works by mimicking glucagon-like peptide-1 (GLP-1), a hormone that slows stomach emptying, increases feelings of fullness, and signals the brain to reduce appetite

What to do next: Include a protein portion in every meal

This article reviews the emerging trend of microdosing GLP-1 drugs, examining potential benefits, risks, and the current lack of scientific evidence supporting this approach

Until more research happens, GLP-1 drugs should only be considered on an individual, case-by-case basis for those with coexisting depression, says Misra

Currently, common clinical GLP-1RAs include exenatide and exenatide-LAR [3440], lixisenatide [4144], beinaglutide [45], liraglutide [4653], semaglutide [5458], albiglutide [5961], dulaglutide [6264], oral semaglutide [58, 6567], PEG-loxenatide [68] and tirzepatide [6873] (Table 1)