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Mechanisms underlying metformin-induced secretion of glucagon-like peptide-1 from the intestinal L cell

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Ozanimod is a selective S1P 1,5 receptor modulator, and etrasimod is a newer-generation S1P 1 , 4,5 receptor modulator

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95% CI 0.90 to 0.74, I 2 58%)

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However, because the medication slows gastric emptying and reduces appetite, many patients naturally find that they prefer smaller portions and may experience discomfort with large, high-fat meals

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