retatrutide phase 2 trial new england journal of medicine The Effect of Retatrutide on Kidney Parameters Phase 2 Trial of Retatrutide

There have been questions around retatrutide tolerance before, and even the first late-stage data show that: the proportion of patients who discontinue therapy due to adverse events is higher than for placebo common problems are nausea, indigestion and other typical gastrointestinal side effects a proportion of patients discontinued treatment due to 'too much' weight loss, which is a signal of strength of effect from a medical perspective but a potential complication from a real-world clinical practice perspective Thus, regulators will be looking not only at absolute efficacy, but also at the safety and long-term tolerability profile - especially in patients who have other chronic diseases in addition to obesity

( Epub 20211021 )

A regulatory submission is under review in Japan

[DOI] [PubMed] [Google Scholar] 21.Su J., et al

The constant mental chatter about when, what, and how much to eat quiets down