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What the Trials Have Actually Shown So Far A phase 2 trial published in the New England Journal of Medicine found that 48 weeks of treatment with retatrutide, an agonist of the GIP, GLP-1, and glucagon receptors, produced substantial reductions in body weight among participants with obesity

Vaginal atrophy is the result of lower estrogen levels, where the vaginal walls become thinner, dryer, and inflamed

Psychopharmacology 240 , 12871298 (2023)

Common side effects include mild nausea, fatigue, headache, or appetite changes, typically subsiding within the first weeks as your body adjusts

[ Rajput, R., Chatterjee, S., & Rajput, M
