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If weight loss is inadequate according to the criteria in the SmPC and NICE guidance, clinicians should reassess the treatment plan rather than adding unproven supplements

Dual-Agonist Mechanism Classification: Tirzepatide is a synthetic peptide drug that operates as a novel dual agonist for the GIP receptor (GIPR) and the GLP-1 receptor (GLP-1R)

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[8] No such EAMS designation has been granted for retatrutide at the time of writing

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