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New England Journal of Medicine (2024) 8

After 15-20 minutes of meal ingestion, plasma concentrations of GLP-1 and GIP increase, stimulating their receptors on pancreatic cells to activate an insulinotropic response that is glucose-dependent and proportional to facilitate the elimination of the absorbed carbohydrate and fat load [4,5]

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COMPOUNDED VERSIONS WARNING: The FDA has issued alerts regarding compounded tirzepatide, warning that these custom formulations may lack the safety, consistency, and efficacy of FDA-approved medications