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It remains unclear whether these neural antiinflammatory actions of GLP-1 medicines require microglial GLP-1R activity

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N Engl J Med 392(5):427437 Pratley RE, Tuttle KR, Rossing P, Rasmussen S, Perkovic V, Nielsen OW et al (2024) Effects of semaglutide on heart failure outcomes in diabetes and chronic kidney disease in the FLOW trial

So the thought is, these patients, their skeleton was used to kind of maintaining one frame, and then all of a sudden, thats being decreased. For gout, Horneff said, rapid weight loss can lead to a temporary spike in uric acid, increasing the risk of gout