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The process boosts glucose-dependent insulin production while reducing glucagon release from the pancreatic -cells, resulting in decreased blood sugar levels and a minimized risk of hypoglycemia because of increased insulin and decreased glucagon secretion [13]

SURPASS-CVOT will not compare tirzepatide to placebo as commonly done

doi: 10.1007/s13340-021-00560-z 90 LiuZZDuanXXYuanMCYuJHuXHanXet al

Association of disrupted circadian rhythmicity with mood disorders, subjective wellbeing, and cognitive function: a cross-sectional study of 91 105 participants from the UK Biobank

Mechanistic studies examining the pathways related to GLP-1RA use with vestibular dysfunction are needed, particularly the role of GIP co-agonism in decreasing vestibular risk