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While consumer aversion to Chipotles higher menu prices may be one factor for the deterioration in sales growth, Advans data and Chipotles actions (in terms of menu innovation) suggest that the rapid update of GLP-1 drugs by more affluent households (which Chipotles out-indexes in) looks to be the larger driver, i.e

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Glucagon-like peptide-1 receptor agonists (GLP-1RAs), such as semaglutide, are widely used in the treatment of metabolic disorders, including type 2 diabetes (T2D) and obesity

In clinical practice, drug selection should therefore prioritize factors such as tolerability, safety profile, adherence, cost, and patient preference rather than expecting major differences in cardiovascular efficacy.

Tara Narula explains what to know about retatrutide and the latest clinical trial results.