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The SURMOUNT-4 trial showed that people who continued tirzepatide after their initial plateau lost an additional 5.5 percent of body weight, while those switched to placebo regained 14 percent

The decision to discontinue semaglutide should be made through shared decision-making with your healthcare provider who can assess your individual circumstances and develop an appropriate plan

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[DOI] [PubMed] [Google Scholar] 192.UK Prospective Diabetes Study (UKPDS) Group Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33) Lancet