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Treatment continuity, patient familiarity, adherence, and cost considerations may favor dose optimization before therapeutic switching

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A discussion on patient perspectives about weight change is based on key preclinical and clinical trials, meta-analyses, and reviews and is supplemented by the authors clinical judgment and research experience in the field

Having demonstrated short-term weight loss with liraglutide in this group of obese adults, we now evaluate safety/tolerability (primary outcome) and long-term efficacy for sustaining weight loss (secondary outcome) over 2 years