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Despite these challenges, the eGFR slope has emerged as a clinically meaningful outcome, with evidence indicating a robust renoprotective effect from the combined use of GLP1-RA and SGLT2i

Using them without proper medical supervision adds risk

One of the more recent representatives of this drug class, and the one that has been shown to exert a superior effect to GLP-1 receptor agonists in humans, is LY3298176/tirzepatide, a synthetic linear peptide molecule containing 39 amino acids (Fig

Compounded medications allow for tailored dosages

Topiramate (sold under the brand name Topamax) is an anticonvulsant medication