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Based on the results of this study, along with findings from the SUSTAIN 6 and 7 trials and the PIONEER 10 trial, our data suggest that the population for whom semaglutide may be appropriate could be expanded to include older patients with elevated HbA1c and higher BMI

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The lowest Phase 2 obesity arm was 1 mg weekly and produced 8.7% weight loss at 48 weeks, but the calculator starts below the trial dose to create a slower adaptation ladder

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