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2 Exenatide is eliminated renally and has been associated with rare occurrences of acute kidney injury

Lixisenatide, a GLP-1R agonist, reduces neurofibrillary tangles and amyloid plaque load, and thereby ameliorates learning memory deficits in APP/PS1 mice (144, 157)

GLP-1 may also directly stimulate glucose uptake in muscle cells (22)
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The incretin, glucagon-like peptide-1 (GLP-1) is an endogenous peptide hormone secreted from intestinal endocrine cells in response to food intake 1
