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The introduction of medications like Wegovy and Zepbound has truly revolutionized the field

Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction
DOI: 10.1001/jama.2021.17295 Wadden, T

Most people plateau around 15 to 20% body weight reduction by month six, though some continue losing gradually beyond this point

Either way, the medication is meant to work alongside lifestyle changesnot instead of them
