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Among the individual GLP-1RAs assessed, the largest reductions in CV risk, HbA1c, and weight outcomes were observed with combination therapy with SGLT2i and once weekly semaglutide for T2D

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With over 50% of GLP-1 users discontinuing due to cost and 36% due to side effects, Nooms low and slow titration strategy could offer a more sustainable path to weight loss

Tirzepatide is a novel, once-weekly, dual GIP and GLP-1 receptor agonist (twincretin) for the treatment of type 2 diabetes