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Moreover, depressed patients show a reduction in synaptic density proteins in response to stress (Kang et al., 2012)
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If approved, it would represent another step-change in outcomes comparable to what tirzepatide was to semaglutide

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This included a pattern mixture model that used comparator-based multiple imputation and AE-determined comparator based multiple imputation, as well as a tipping-point analysis (Table 21)
