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Description
Amylin + GLP-1 combination (CagriSema) is Novos most differentiated next-generation bet, targeting a different receptor class (AMYR/CALCR) for potentially additive weight loss

Increase to 0.5 mg, then 1 mg, then 1.7 mg, then 2.4 mg

for weight management sometime in 2026

Yes appetite suppression generally becomes more noticeable as your semaglutide dosage increases, up to the target therapeutic level

Remaining readouts, TRIUMPH-3 and the other sub-trials, are anticipated through 2026 to mid-2027, while TRIUMPH-Outcomes (the cardiovascular outcomes trial) follows a longer timeline through 2028
