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Lastly, the results of a very recent systematic review and network meta-analysis aimed to compare the effects of oral antidiabetic drugs in endocrine and metabolic profiles in patients with PCOS confirmed that metformin was more beneficial in reducing serum total testosterone, whereas GLP-1RA + metformin reduced FAI more effectively [24]

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A balanced assessment of convenience, potential side effects, and the need for more robust clinical data is crucial when considering this treatment option

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