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Important toxicologic components include serotonin, amine oxidase, phospholipase A, substances promoting the release of bradykinin, helodermin, hyaluronidase, and exendin 4

Based on the available evidence, cagrilintide appears to have a more favorable body composition profile, though the magnitude of difference between the two compounds remains to be determined through direct comparison studies

They were randomly assigned in a 2:1 ratio, to 68 weeks of treatment with semaglutide (at a dose of 2.4 mg) or placebo, plus lifestyle intervention

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