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The report included a statement from the FDA indicating that it had received reports of gastroparesis with semaglutide and liraglutide, some of which documented the adverse event as not recovered after discontinuation of the respective product at the time of the report. The FDA did indicate at the time that it had been unable to determine whether the medications directly caused the injuries

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This is particularly important when switching from a GLP-1 based therapy to non-GLP-1 options, because the metabolic adjustment can affect blood sugar regulation, blood pressure, and heart rate in ways that warrant monitoring

The addition of GIP enhances the fat-burning effects, making this medication particularly effective for sustained weight loss