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Nazarzadeh M, Bidel Z, Canoy D, Copland E, Bennett DA, Dehghan A, et al

This surgery isnt an option for everyone

Adherence and persistence among patients with type 2 diabetes initiating dulaglutide compared with semaglutide and exenatide BCise: 6-month follow-up from US real-world data

Semaglutide (Wegovy/Ozempic) is the closest currently available alternative, producing 14-16% average weight loss compared to tirzepatide at 18-22%

Studies on GLP-1 receptor agonists suggest that a third or more of the weight lost may come from lean muscle tissue
