semaglutide and insulin might be a key for breaking the vicious cycle of metabolically associated fatty liver disease spectrum? Semaglutide - Wikipedia

GLP-1 agonists are contraindicated in pregnancy and breastfeeding

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The side effect profiles of phentermine and GLP-1 medications are fundamentally different because the drugs operate through entirely different mechanisms, and understanding these differences is essential for making an informed choice

Choose Safety Profile Adverse reactions reported in 3% of Wegovy 2.4 mg injection-treated adolescent patients aged 12 years and older with obesity and more frequently than with placebo 1 Gastrointestinal disorders were the most frequent adverse events with Wegovy ( 62% vs 42% with placebo) 2.3% of patients treated with Wegovy vs 1.5% of patients who received placebo discontinued treatment as a result of gastrointestinal adverse events 6 Mean increases in resting heart rate of 1.2 beats per minute from baseline were observed with patients taking Wegovy vs a decrease of 2.3 beats per minute with placebo 6 Adverse reactions with Wegovy treatment in pediatric patients aged 12 years and older were similar to those reported in adults

Side Effects Nausea Vomiting Diarrhea Constipation Headache Fatigue Dizziness Low blood sugar (hypoglycemia) Injection site pain Mild side effects such as nausea or fatigue generally subside with time or a decreased dose